| Palmar erythema | |
|---|---|
| Classification and external resources | |
| ICD-10 | L53.8 (ILDS L53.840) |
| ICD-9 | 695.0 |
| DiseasesDB | 24070 |
Palmar erythema is reddening of the palms at the thenar and hypothenar eminences.[1]:139
It is associated with various physiological as well as pathological changes, the principal one of which is portal hypertension. It is also seen in patients with liver dysfunction, such as chronic liver disease (chronic hepatitis [2] ), and also in pregnant women. Palmar erythema may also be the result of thyrotoxicosis and dermatoses such as eczema or psoriasis, and is related to deep telangiectasias. It may also be a normal finding.
Because circulating levels of estrogen increase in both cirrhosis and pregnancy, estrogen was thought to be the cause for the increased vascularity. More recently, nitric oxide has been implicated in the pathogenesis of palmar erythema.
Palmar erythema occurs in about 30% of patients with rheumatoid arthritis especially those with elevated hemoglobin levels [3].
Palmar erythema can also be seen in Coxsackievirus A infection (hand, foot and mouth disease), Rocky Mountain Spotted Fever, and secondary Syphilis. [4].
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